Paracetamol and its Influence on the Opioid Requirement in Sufficient Pain Management in the ED

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON22636

Enrollment

168

Registered

2018-01-17

Start date

2018-01-22

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid use, pain

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - patients 18 years or older presenting to the ED in the AMC - an NRS of 4 or higher during presentation - patients having received an opioid prehospitally (usually in the ambulance) or in the ED

Exclusion criteria

Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - hepatic dysfunction - not capable of reporting their NRS during presentation - chronic use of analgesics

Design outcomes

Primary

Measure	Time frame
The main study endpoint is the opioid requirement in Morphine Equivalent Units (MEU) between individual subjects who received additional paracetamol and those who did not.	—

Secondary

Measure	Time frame
Secondary outcome is the NRS measured an hour after administration of the opioid and at discharge, between individual subjects who received additional paracetamol at the ED and those who did not.	—

Contacts

Public ContactM.L. Ridderikhof

Promovendus Anesthesiologie & Traumatologie Afdeling Spoedeisende Geneeskunde Academisch Medisch Centrum Meibergdreef 9

M.L.Ridderikhof@amc.uva.nl020-5663333

Outcome results