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Long-term outcomes of total hip and knee arthroplasties.

Longitudinal Leiden Orthopaedics Outcomes of Osteo- Arthritis Study. (LOAS)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON22630
Enrollment
4500
Registered
2012-03-13
Start date
2012-05-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis, arthritis, total hip prosthesis, total knee prosthesis

Interventions

The investigational product is the standard procedure (usual clinical care) for total hip replacement or total knee replacement.

Sponsors

LUMC, Leiden Rijnland Ziekenhuis, Leiderdorp Diaconessenhuis, Leiden Groene hart ziekenhuis, Leiden Lange land ziekenhuis, Zoetermeer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients who are scheduled for primary total hip or total knee surgery or revision surgery; 2. Are able to complete questionnaires, either on paper or electronically; 3. Patients > 18 years of age.

Exclusion criteria

Exclusion criteria: 1. No informed consent signed; 2. Insufficient Dutch language skills; 3. Physical or mental status not allowing participation.

Design outcomes

Primary

MeasureTime frame
1. Knee or hip functioning (HOOS/KOOS); 2. Physical activity (SQUASH questionnaire, accelerometer); 3. Work status; 4. Quality of life (SF-12 and EQ-5D); 5. Patient satisfaction; 6. Health care usage; 7. Radiological outcome (post-operative femorotibial angle (knee) and alignment of the stem and inclination of the cup (Hip) and post-operative complications.

Secondary

MeasureTime frame
1. Sociodemographic characteristics (age, sex); 2. Comorbidities (comorbidity questionnaire, Charnley classification and ASA classification); 3. Frailty (>70 years of age: Groningen Frailty Index); 4. Pre-operative use of pharmacological and non-pharmacological treatment for hip or knee pain; 5. Outcome expectations (the New York Hospital for Special Surgery Questionnaire); 6. Preoperative radiographic damage (Kellgren score, Femorotibial angle and alignment of the stem and inclination of the cup) and hand grip strength.

Contacts

Public ContactC. Tilbury

Postzone J11R Postbus 9600

c.tilbury@lumc.nl+31 (0)71 5263606

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)