Post-mortem radiology. Whole-body MRI. Whole-boy CT. Whole-body imaging. CT-guided biopsy. MIA: diagnostic performance. Image-guided biopsy. Stereotactic brain biopsy. Conventional autopsy. Alternative autopsy.
Conditions
Interventions
We performed MIA followed by CA the following day. Both the MIA investigators and CA pathologists who performed the autopsy received the same clinical information and were blinded to each other's find
Sponsors
Erasmus university medical center
Eligibility
Inclusion criteria
Inclusion criteria: Deceased adult patients, written informed consent from next of kin, availability of imaging equipments and technologists
Exclusion criteria
Exclusion criteria: forensic causes of death, known or suspected “high-risk” infected cadavers (hepatitis C, human immunodeficiency virus, tuberculosis), open abdominal wounds and body size too large for imaging equipment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Agreement between MIA and CA for cause of death and sensitivity and specificity of major and overall findings | — |
Secondary
| Measure | Time frame |
|---|---|
| - Comparing CA and MIA of the brain. - Estimating the amount of information lost by MIA, compared to the CA and finding out if the expected increase of autopsies performed compensates for this loss. - Comparing costs of the MIA versus CA. | — |
Contacts
Public ContactJ.W. Oosterhuis
Outcome results
None listed