Neonatal late-onset sepsis
Conditions
Interventions
None listed
Sponsors
Erasmus MC – Sophia Children’s Hospital
Eligibility
Inclusion criteria
Inclusion criteria: A gestational age of 24 weeks up to and including 31 weeks at the time of inclusion. A pulse oximeter as part of regular care. Written informed consent.
Exclusion criteria
Exclusion criteria: A gestational age of 32 weeks or more at the time of inclusion. Skin condition contraindicating transcutaneous measurements. Absence of written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The relation between transcutaneous blood gas levels and neonatal sepsis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of the effect of patient age and time since birth on measurement accuracy. The influence of ventilation and hemodynamic as measured by ventilation parameters, patient monitoring parameters, and registration of applied vasopressors on skin perfusion. Correlation of sensor value deviations and drift from blood gas sample values between measured transcutaneous blood gas levels and heating power to analyze the effects of skin temperature and vascularization on measurement accuracy. Assessment of the measurement quality and accuracy in patients with microcirculatory impairment. Determine the effect of the sensor location on the level and reliability of the measurements. Determine the relation between sepsis indicated by transcutaneous blood gas monitoring and questionnaires recording the clinical considerations for blood culturing by the attending neonatologist. | — |
Contacts
Public ContactMaud Hoofs
Erasmus MC
Outcome results
None listed