The effect of electrical neurostimulation on collateral perfusion during acute coronary occlusion.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON22491

Enrollment

Registered

2007-04-18

Start date

2006-01-10

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. Angina

Interventions

The intervention was electrical neurostimulation, during 5 minutes before and during the 1-minute ischemic episode. Within a patient we measured during the 1-minute ischemic episode the collateral per

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with stable angina; 2. Evidence of myocardial ischemia; 3. Planned for elective percutaneous coronary intervention.

Exclusion criteria

Exclusion criteria: 1. Recent myocardial infarction; 2. Prior coronary artery bypass grafting; 3. Undtable angina; 4. Conduction disturbances; 5. Pacemaker; 6. Internal cardio defibrillator.

Design outcomes

Primary

Measure	Time frame
The primary endpoint was collateral perfusion, the Pw/Pa ratio. This was measured during a 1-minute balloon inflation during PCI. The Pw/Pa ratio was measured in each patient during two ischemic episodes. To compare the Pw/Pa ratio with and without electrical neurostimulation. The Pw/Pa ratio is measured intracoronary, using a pressure wire.	—

Contacts

Public ContactJ. Vries, de

Thoraxcenter UMCGroningen Hanzeplein 1

j.de.vries@thorax.umcg.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)