In mechanically ventilated patients, endotracheal suctioning will be performed when indicated. During two 6-month periods all ES procedures will be performed with either OSS or CSS. After 6 months, 1 month of wash out/wash in is planned, during which the system is changed.
Conditions
Interventions
Endotracheal suctioning as indicated, according to a protocol, with either CSS or OSS.
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: All adult ICU patients receiving MV will be included and, during 6 months, be subjected to the same ES-procedure.
Exclusion criteria
Exclusion criteria: No exclusion criteria. Preference of ES system is often based on assuptions, there is currently no scientific evidence available to prefer one system over the other.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of cross-transmission (primary endpoint), defined as acquired colonization with a genetically identical pathogen with an epidemiological linkage to a potential source patient. | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of stay in ICU, antibiotic use, cardio-respiratory adverse events (hypoxemia, cardiac arrhythmia, damage to respiratory mucosa), mortality, the incidence of VAP and cost-efficacy. | — |
Contacts
Public ContactI.P. Jongerden
P.O. Box 85500
Outcome results
None listed