Magnetic Resonance Imaging, Cine Cystic Adenomatoid Malformation of Lung, Congenital
Conditions
Interventions
MRI
Lungfunction test
Sponsors
Erasmus Medical Center, Sophia Children's Hospital
Eligibility
Inclusion criteria
Inclusion criteria: - Radiological or if resected pathological diagnosis of CPAM - Enrolment in CHIL follow-up program - Age ≥ 8 years and < 18 years at the start of the study - Signed informed consent by parents and/or patient
Exclusion criteria
Exclusion criteria: - Contra- indications for MRI - Cognitive impairment preventing adherence to breathing instructions - Presence of associated anomalies in chest cavity which might skew results according to primary physician - Claustrofobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoints are the MRI features of the lungs both before and after resection of CPAM and its correlation to lung function. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoint is the MRI scan protocol in which optimal imaging of lung parenchyma and abnormalities is achieved. Furthermore, the difference in lung function between surgically and conservatively treated patients as well as their relation to imaging characteristics including volume of the abnormality. | — |
Contacts
Public ContactH.A.W.M. Tiddens
Erasmus Medical Center, Sophia Children’s Hospital Rotterdam, Department of Pediatric Pulmonology, Dr. Molewaterplein 60
Outcome results
None listed