Colloid Oncotic Pressure as indicator of hemodilution in cardiac surgery with cardiopulmonary bypass

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON22437

Enrollment

Registered

2020-11-18

Start date

2020-12-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary disease, cardiac valve disease

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: • Informed consent • Patients undergoing elective cardiac surgery

Exclusion criteria

Exclusion criteria: • Emergency operations • Patients with previous heart surgery • Patients undergoing elective thoracic aortic surgery.

Design outcomes

Primary

Measure	Time frame
•To determine the changes in COP between different priming fluids during cardiac surgery with CPB	—

Secondary

Measure	Time frame
• Is the serum albumin level correlated with the level of COP during cardiac surgery with CPB? • Is the change of COP during cardiac surgery with CPB associated with a change in extravascular fluid shift (positive fluid balance, weight gain, mean arterial pressure)? • Is the change of COP during cardiac surgery with CPB associated with intravascular hemodilution (hemoglobin, hematocrit, blood product use)? • Is the change of COP during cardiac surgery with CPB associated with blood loss and hemostasis (platelet count, fibrinogen, use of coagulation factors concentrate)?	—

Measure

Time frame

• Is the serum albumin level correlated with the level of COP during cardiac surgery with CPB? • Is the change of COP during cardiac surgery with CPB associated with a change in extravascular fluid shift (positive fluid balance, weight gain, mean arterial pressure)? • Is the change of COP during cardiac surgery with CPB associated with intravascular hemodilution (hemoglobin, hematocrit, blood product use)? • Is the change of COP during cardiac surgery with CPB associated with blood loss and hemostasis (platelet count, fibrinogen, use of coagulation factors concentrate)?

—

Contacts

Public ContactAnne Beukers

Amsterdam UMC, VUmc location

a.beukers@amsterdamumc.nl0624543517

Outcome results