Hepatic Uveal Melanoma Metastases
Conditions
Interventions
ICG will be administered 24hours before surgery. During laparoscopic surgery, liver metastases will be visualised using near-infrared fluorescence imaging and standard liver resection will be performe
Sponsors
Leiden University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with uveal melanoma liver metastasis that are eligible for resection; 2. Age between 18 and 80 years old.
Exclusion criteria
Exclusion criteria: 1. No history of allergy to iodine, shellfish, indocyanine green, human serum albumin and/or history of hyperthyroidism or severe renal impairment; 2. Patient pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasiility of Intra-operative identification of liver metastases. | — |
Secondary
| Measure | Time frame |
|---|---|
| Identification rate; defined as the number of tumours that were identified with the fluorescent signal of ICG during operation, compared with the number of microscopically Tumor to background ratio between different doses of ICG injected and different time intervals injected. | — |
Contacts
Public ContactC.J.H. Velde, van de
Leiden University Medical Center (LUMC), Department of Surgical Oncology, P.O. Box 9600
Outcome results
None listed