Patients with an increased risk for polyps or cancer
Conditions
Interventions
High resolution white light endoscopy versus Autofluorescence endoscopy.
Sponsors
Academic Medical Center , Department of Gastroenterolgy.
Eligibility
Inclusion criteria
Inclusion criteria: 1. Previous adenomatous polyp (polyp-surveillance); 2. Previous adenocarcinoma of the colon for which a partial colectomy was performed; 3. Hereditary non-polyposis colorectal cancer (either genetically proven by a mutation in one of the mismatch repair genes or with a clinical diagnosis according to the Amsterdam II criteria [14]); 4. Positive family history for CRC: a first-degree family-member fullfills one of the revised Bethesda criteria.
Exclusion criteria
Exclusion criteria: 1. Familiar adenomatous polyposis; 2. History of inflammatory bowel disease; 3. Severe coagulopathy; 4. Age less than 18 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The sensitivity of high resolution white light endoscopy will be compared to that of AFI for detection of polyps and cancer in the colon. | — |
Contacts
Public ContactEvelien Dekker
Academic Medical Center (AMC) Department of Gastroenterology and Hepatology P.O. Box 22660
Outcome results
None listed