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TransplantLines Food and Nutrition Biobank and Cohort Study (TxL-FN)

Renal Sensing of the Acidifying Effect of Sulphur-containing Amino Acids: Consequences for the Relation Between Protein Intake and Blood Pressure in Renal Transplant Recipients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON22374
Enrollment
1000
Registered
2016-06-21
Start date
2008-11-21
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Short-term (1-year) results of renal transplantation are now excellent (over 95%). Long-term (10-year and longer) results are, however, still disappointing. Where most research has focused on immunosuppression and infections, we hypothesize that due to poor homeostatic capacity and necessary use of immunosuppressive and other drugs, renal transplant recipients are much more susceptible to poor dietary habits and exposure to potentially toxic contaminants than people of the general population, an

Interventions

Sponsors

University Medical Center Groningen
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: More than one year after transplantation, prognosis > 1 year, stable outpatients situation

Exclusion criteria

Exclusion criteria: Acute illnesses, fever, current hospitalisation

Design outcomes

Primary

MeasureTime frame
Graft failure and all-cause mortality

Secondary

MeasureTime frame
Cause-specific graft failure Cause-specific mortality Change in renal function Development of new-onset diabetes after transplantation

Contacts

Public ContactS.J.L. Bakker

Department of Internal Medicine - University Medical Center Groningen

s.j.l.bakker@umcg.nl+31-50-3616161

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)