POC whole blood thrombin generation

Clinical validation of the point of care whole blood thrombin generation assay.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON22346

Enrollment

100

Registered

2013-10-08

Start date

2013-10-14

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac surgery (hart chirurgie), thrombin generation (trombin vorming), coagulation (stolling)

Interventions

observational study investigating coagulation capacity by the means of whole blood thrombin generation.

Eligibility

Inclusion criteria

Inclusion criteria: All consecutive patients after cardiac surgery during a period of 18 weeks.

Exclusion criteria

Exclusion criteria: age under 18 yrs. known coagulation disorder.

Design outcomes

Primary

Measure	Time frame
Whole blood thrombin generation results compared to automated plasma thrombin generation results	—

Secondary

Measure	Time frame
1. lab results (ROTEM, whole blood TG, classic coagulation tests) 2. clinical association with bleeding (amount of blood loss, fluid infusion and use of blood products)	—

Contacts

Public ContactM.D. Lancé

dept of anesthesiology MUMC+ P.Debeyelaan 25

marcus.lance@mumc.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)