iron deficiency, children, diabetes type 1, HbA1c
Conditions
Interventions
No intervention.
Sponsors
Juliana Children's Hospital/Haga Hospital, the Hague, the Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: - children, aged 1 to 18 years. - diagnosis of DM for at least one year and based on internationally accepted definitions (Craig 2009).The period of one year is chosen to exclude children who are still in their honeymoon phase and who might use therefore less insulin. - the need for the blood draw at the check-up moment - written informed consent from parents/guardian and children themselves if >12 years.
Exclusion criteria
Exclusion criteria: - known infections in the last four weeks - C-reactive protein equal or above 5 mg/L - oncologic disorder - iron supplementation during the last six weeks - blood transfusion during the last six months - known hemoglobinopathies - congenital malformations
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the iron status of children with diabetes mellitus type 1, based on several iron status parameters. ID will be classified according to the WHO criteria for ID (serum ferritin < 12 or < 15, depending on the age). | — |
Secondary
| Measure | Time frame |
|---|---|
| - to identify determinants of ID & IDA in children with DM type 1. - to investigate the influence of ID(A) on HbA1c levels. | — |
Contacts
Public ContactM.D. Akkermans
Outcome results
None listed