beer, wine, spirits, diuretic effect
Conditions
Interventions
During each treatment, subjects are randomly exposed to one condition: beer (lager), non-alcoholic beer, red wine, non-alcoholic red wine, spirits (jenever) or water. An amount equal to 30 g of alcoho
Sponsors
Wageningen University
Eligibility
Inclusion criteria
Inclusion criteria: - Age between 60-75 yrs - Male gender - BMI between 20-30 kg/m2 - Normal renal function (normal plasma concentrations of creatinine and urea) - Used to drink alcoholic beverages - Healthy (as judged by the participant)
Exclusion criteria
Exclusion criteria: - Usage of an energy restricted diet during the last two months - Weight loss or weight gain of 5 kg or more during the last two months - Having endocrine, bowel or neurological disorders that could interfere with outcome variables - Usage of systemic medication that could interfere with outcome variables (e.g. diuretics) - Being allergic/intolerant for products under study - Smoking more than seven cigarettes/cigars per week - Drinking on average more than 21 alcoholic beverages a week - Being an alcoholic or history of alcoholism - Family history of alcoholism (loss of control, tolerance or withdrawal symptoms towards alcohol in direct family) - Current participation in other scientific research - Being employee, thesis student or intern of the Division of Human Nutrition (WUR)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in cumulative fluid balance between the three alcoholic beverages and their non-alcoholic counterparts. In the end conclusions can be drawn on whether or not there is a difference in (cumulative) urine output between beer (beer minus non-alcoholic beer), red wine (red wine minus non-alcoholic red wine) and spirits (spirits (jenever) minus water). | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative differences for urinary sodium, potassium and osmolality, comparing the samples before lunch, 1, 2, 3 and 4 hours after lunch and after lunch until the next morning. Urine sodium, potassium and urine osmolality testing is performed to evaluate electrolyte and water balance (status of hydration). | — |
Contacts
Public ContactM. Tieland
Wageningen University & Research centre
Outcome results
None listed