Musculoskeletal complaints in patient with congenital disorders of the hand and arm.

Musculoskeletal complaints in congenital anomalies of the upper extremity.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON22283

Enrollment

200

Registered

2017-12-22

Start date

2018-01-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal complaints Musculoskeletal Pain (Pubmed MeSh Congenital anomalies of the upper extremity Upper Extremity Deformities, Congenital Adult Male Female Questionnaire Cross-sectional study Overbelastingsklachten

Interventions

None

Eligibility

Inclusion criteria

Inclusion criteria: • Patients and healthy subjects aged 18 years or older. • Sufficient knowledge of the Dutch language to fill out the questionnaire • A large congenital anomaly of the upper extremity classified by the “OMT CLASSIFICATION OF CONGENITAL HAND AND UPPER LIMB ANOMALIES” as follows: I. MALFORMATIONS A. Abnormal axis formation/differentiation—entire upper limb 1. Proximal-distal axis i…Brachymelia with brachydactyly ii..Symbrachydactyly a) Poland syndrome iv. Intersegmental deficiency a) Proximal (humeral – rhizomelic) b) Distal (forearm – mesomelic) c) Total (Phocomelia) v. Whole limb duplication/triplication 2. Radial-ulnar (anterior-posterior) axis i…..Radial longitudinal deficiency - Thumb hypoplasia (with proximal limb involvement) ii….Ulnar longitudinal deficiency iii...Ulnar dimelia iv...Radioulnar synostosis v….Congenital dislocation of the radial head vi…Humeroradial synostosis - Elbow ankyloses vii..Madelung deformity 3. Dorsal-ventral axis i…..Ventral dimelia a) Furhmann/Al-Awadi/Raas-Rothschild syndromes b) Nail Patella syndrome ii….Absent/hypoplastic extensor/flexor muscles 4. Unspecified axis i…..Shoulder a) Undescended (Sprengel) b) Abnormal shoulder muscles c) Not otherwise specified ii…..Arthrogryposis B. Abnormal axis formation/differentiation— hand plate 1. Proximal-distal axis i…..Brachydactyly (no forearm/arm involvement) ii….Symbrachydactyly (no forearm/arm involvement) 2. Radial-ulnar (anterior-posterior) axis i…..Radial deficiency (thumb - no forearm/arm involvement) ii....Ulnar deficiency (no forearm/arm involvement) v….Ulnar dimelia (mirror hand – no forearm/arm involvement) 3. Dorsal-ventral axis i…..Dorsal dimelia (palmar nail) ii….Ventral (palmar) dimelia (including hypoplastic/aplastic nail) 4. Unspecified axis i…..Soft tissue d) Distal arthrogryposis iii. Complex a) Complex syndactyly b) Synpolydactyly— central c) Cleft hand d) Apert hand e) Not otherwise specified II. DEFORMATIONS C. Not otherwise specified III. DYSPLASIAS A. Hypertrophy 1. Whole limb i…..Hemihypertrophy ii….Aberrant flexor/extensor/intrinsic muscle 2. Partial limb i…..Macrodactyly ii….Aberrant intrinsic muscles of hand

Exclusion criteria

Exclusion criteria: • Comorbidity severely affecting upper extremity function • Amputation of the upper extremity • Transverse reduction defects of the upper extremity classified by the “OMT CLASSIFICATION OF CONGENITAL HAND AND UPPER LIMB ANOMALIES” as follows: I. MALFORMATIONS A. Abnormal axis formation/differentiation—entire upper limb 1. Proximal-distal axis b) Whole limb excluding Poland syndrome iii. Transverse deficiency a) Amelia b) Clavicular/scapular c) Humeral (above elbow) d) Forearm (below elbow) e) Wrist (carpals absent/at level of proximal carpals/at level of distal carpals ) (with forearm/arm involvement) f) Metacarpal (with forearm/arm involvement) g) Phalangeal (proximal/middle/distal) (with forearm/arm involvement) B. Abnormal axis formation/differentiation— hand plate 1. Proximal-distal axis iii…Transverse deficiency (no forearm/arm involvement) a) Wrist (carpals absent/at level of proximal carpals/at level of distal carpals) b) Metacarpal c) Phalangeal (proximal/middle/distal) II. DEFORMATIONS A. Constriction ring sequence • ‘Minor’ congenital anomalies classified by the “OMT CLASSIFICATION OF CONGENITAL HAND AND UPPER LIMB ANOMALIES” as follows: B. Abnormal axis formation/differentiation— hand plate 2. Radial-ulnar (anterior-posterior) axis iii…Radial polydactyly iv…Triphalangeal thumb vi…Ulnar polydactyly 4. Unspecified axis i…..Soft tissue a) Syndactyly b) Camptodactyly c) Thumb in palm deformity ii. Skeletal deficiency a) Clinodactyly b) Kirner’s deformity c) Synostosis/symphalangism (carpal/metacarpal/phalangeal) II. DEFORMATIONS B. Trigger digits

Design outcomes

Primary

Measure	Time frame
Patient reported musculoskeletal complaints Pain reported on visual analog scale. Items on pain in SF-36 questionnaire.	—

Secondary

Measure	Time frame
Reported upper extremity function UEWD-R questionnaire PDI questionnaire DASH questionnaire	—

Contacts

Public ContactMJJ Koenis

UMCG

m.j.j.koenis@umcg.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)