Respiratory tract infections, gastrointestinal tract infections
Conditions
Interventions
Group 1: Standard Growing up milk
Group 2: Growing up milk + new fat blend
Group 3: Growing up milk + new fat blend + probiotic 1
Group 4: Growing up milk + new fat blend + probiotic 2.
Sponsors
FrieslandCampina Innovation Infant & Toddler Nutrition
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy Indonesian children; 2. Between 1 and <3 years of age; 3. Non-breastfed.
Exclusion criteria
Exclusion criteria: 1. In sick condition 1 month before the start of the study; 2. Receiving antibiotics treatment 2 weeks before the study starts; 3. Breastfeeding 2 months prior to the start of the intervention period; 4. Consumption of pre-, pro- or synbiotic products at least 2 weeks prior to the intervention; 5. Symptoms of chronic/congenital diseases and disabilities, suspected Tuberculosis by clinical examination, and/or history of allergic diseases; 6. Use of medication that can interfere with the study 2 months before the start, such as strong anti-inflammatory drugs; 7. History of lactose intolerance; 8. History of cow’s milk allergy; 9. Siblings of already included children that are living in the same household, except if it is a twin sibling; 10. Participation in another clinical trial at the same time or 2 months prior to the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of respiratory tract and gastrointestinal tract infection episode. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of infection; 2. Severity of infection; 3. Physical growth; 4. Rotavirus prevalence; 5. Gut microflora; 6. Mucosal inflammation. | — |
Contacts
Public ContactMarjolijn C.E. Bragt - van Wijngaarden
FrieslandCampina Innovation Infant & Toddler Nutrition P.O. Box 226
Outcome results
None listed