Treatment of anxiety disorders in children with Autism Spectrum Disorders (ASD).

Treatment of anxiety disorders in children with autistic-spectrum Disorders (ZonMw). Cognitive Behavioral therapy for anxiety disorders in children with and without developmental disorders (MEC).

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON22241

Enrollment

200

Registered

2011-05-25

Start date

2006-02-03

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ASD refers to conditions that share a core triad of impairments consisting of qualitative impairments in social interaction, verbal and non-verbal communication, and repetitive and stereotyped patterns of interest and behavior (APA, 2001). ASD is estimated to occur in 0.6% of the population (Fombonne, 2005), however, there is considerable heterogeneity of symptom presentation. Furthermore, psychiatric comorbidity is very common among children with ASD (e.g. De Bruin et al., 2007). Of interest to

Interventions

The study has two arms. The first arm of the study consists of a comparison between children with anxiety disorders, with and without ASD. These children receive the same intervention (CBT). The secon

Bögels, 2008) consists of 15 sessions within approximately 3 months. There are 12 child sessions and three parent sessions. Its main ingredients are: psycho-education about anxiety, challenging anxiou

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children, aged 7-18, must have at least one anxiety disorder (all anxiety disorder are included), according to parent and/or child report; 2. At least one parent is willing to participate in treatment and research.

Exclusion criteria

Exclusion criteria: 1. Acute suicidal behavior; 2. Untreated psychotic disorder; 3. IQ below 70; 4. DSM-IV V-code of current sexual or physical abuse; 5. Having had CBT for anxiety disorders in the past year.

Design outcomes

Primary

Measure	Time frame
1. Diagnostic status: whether the child still meets criteria for its (primary) anxiety disorder (ADIS); 2. Anxiety symptomatology (SCARED); 3. Quality of Life (QoL; EQ-5D); 4. Costs (measured by a retrospective costs-questionnaire).	—

Secondary

Measure	Time frame
1. General psychopathology (CBCL); 2. ASD-related symptoms (CSBQ); 3. Family Functioning (FFS & FAST); 4. Parental rearing behavior (CDQ); 5. Parental anxiety (SCARED); 6. Parental quality of life (EuroQol); 7. Attachment (AQ).	—

Contacts

Public ContactBonny Steensel, van

University of Amsterdam Nieuwe Prinsengracht 130

f.j.a.vansteensel@uva.nl+31 (0)20 5251316

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)