low muscle strength, low muscle mass, low physical fitness, sarcopenia, aging process
Conditions
Interventions
All subjects will receive a 4 week intervention program consisting of:
1) an exercise program (combination of resistance and aerobic exercises during supervised exercise sessions, and a home-based ad
Sponsors
Ziekenhuis Gelderse Vallei
Eligibility
Inclusion criteria
Inclusion criteria: - Aged 55 to 75 years. - Not meeting the Dutch Norm for Health-enhancing Physical Activity ('Nederlandse Norm Gezond Bewegen'). - No participation in any structured or regular exercise training programs for the last 3 months.
Exclusion criteria
Exclusion criteria: - Allergic or sensitive for milk proteins, or lactose intolerant. - Diagnosed with renal insufficiency. - On a diet which affects protein intake (i.e. advices of an increase, decrease or type of protein (intake)). - Having known contraindications for exercise. - Diagnosed with cancer for which currently treated. - Having a contraindication to MRI scanning (including, but not limited to): o pacemakers and defibrillators o intraorbital or intraocular metallic fragments o ferromagnetic implants o claustrophobia - Participation in another intervention trial. - Unable to understand Dutch.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of this study is the change in isometric quadriceps strength (Biodex). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters are changes in quadriceps muscle mass (MRI and ultrasound), handgrip strength (dynamometer), power of the lower limb (chair rise time test), physical fitness (Åstrand-Rhyming test), habitual physical activity (accelerometer) and daily protein intake (24h recall questionnaire). | — |
Contacts
Public ContactMargot de Regt
Ziekenhuis Gelderse Vallei - Afdeling Fysiotherapie
Outcome results
None listed