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Evaluation of the relationship between AGEs and treatment outcome of vitrectomy in PDR patients

Evaluation of the relationship between AGEs and treatment outcome of vitrectomy in PDR patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON22139
Enrollment
70
Registered
2020-07-23
Start date
2020-08-28
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes mellitus, diabetic retinopathy

Interventions

skin autofluorescence measurement (non invasive)

Sponsors

University of Groningen
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Willingness to participate. • Age: >18 years. • Patients diagnosed with PDR who have undergone or will undergo vitrectomy at the UMCG. • Patients who have at least 1-year follow-up with BCVA after vitrectomy at the UMCG will be included.

Exclusion criteria

Exclusion criteria: • Unwillingness to participate. • Dark coloured skin (Fitzpatrick type V or VI), which will impair the reliability of the autofluorescence measurement. • Skin abnormalities on both arms that will impair the reliability of the autofluorescence measurement. • Local or general active infection or inflammatory disease. • Known renal disease, current dialysis treatment, or a history of renal transplantation. • Patients with high myopia (>6 diopters), glaucoma, combined retinal disease, prior vitreoretinal surgery.

Design outcomes

Primary

MeasureTime frame
the relation between skin AF and visual outcome of PDR patients at 1 year after vitrectomy.

Secondary

MeasureTime frame
re-vitrectomy rate within the first year.

Contacts

Public ContactL.I. Los

University Medical Center Groningen

l.i.los@umcg.nl050-3612510

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)