Alzheimer's disease
Conditions
Interventions
Multicomponent intervention consisting of a combination of measures aimed at prevention of cerebrovascular disease (platelet aggregation inhibitors, statin, strict regulation of blood pressure, diabet
Sponsors
ZONMw Doelmatigheidsonderzoek
Eligibility
Inclusion criteria
Inclusion criteria: Patients with early Alzheimer's disease according to clinical criteria, that have on MRI either cerebral infarcts or significant white matter abnormalities.
Exclusion criteria
Exclusion criteria: 1. Severe dementia; 2. Limited life expectancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in impairments after two years of follow up in activities of daily living as measured by the Interview for Deterioration in Daily life in dementia (IDDD). | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in cognitive functioning, behavioral abnormalities, blood pessure, body weight. New lesions on MRI after two years. | — |
Contacts
Public ContactW.A. Gool, van
Academic Medical Center (AMC), Department of Neurology (H2-217), P.O. Box 22660
Outcome results
None listed