COVID-19
Conditions
Interventions
None listed
Sponsors
Amphia Hospital Breda
Eligibility
Inclusion criteria
Inclusion criteria: In order to evaluate clinical specificity, symptomatic adults (=18 years) who present at a participating GGD test centre for a COVID- 19 test will be included. In order to evaluate clinical sensitivity, symptomatic adults (=18 years) who were tested positive with qRT-PCR in a participating GGD test centre will be included.
Exclusion criteria
Exclusion criteria: Age <18 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| For part one of the study the primary outcome was the VRD clinical sensitivity and specificity compared to qRT-PCR. For the second part of the study the primary outcome was VRD clinical sensitivity compared to qRT-PCR stratified by Ct-value category (Ct<20, Ct20-25, Ct25-30 and Ct=30) and time since symptom onset (< 7 days, = 7 days). | — |
Secondary
| Measure | Time frame |
|---|---|
| Furthermore, overall positive predictive value (PPV) and negative predictive value (NPV) were calculated for a range of population prevalence (0.1%, 1.0%, 5%, 10%). In both parts of the study concordance between VRD analysis with the VA and visual interpretation were evaluated and compared with qRT-PCR results. Furthermore the practical applicability will be evaluated. | — |
Contacts
Public ContactNathalie Van der Moeren
Microvida Amphia Hospital Breda
Outcome results
None listed