Type 1 diabetes.
Conditions
Interventions
A CGM sensor (Dexcom G5 Mobile CGM®) will be inserted 1 day prior to study entry. All patients and their parents will receive training in CGMS day-to-day management.
After insertion and education on
Sponsors
Haga Hospital
Leyweg 275, 2545 CH The Hague,
The Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: - Children with type 1 diabetes who have been diagnosed for > 1 year. - Age between 7 and 17 years. - Glycated haemoglobin (HbA1c) <8.5% (69 mmol/mol). - BMI < +1.8 Standard Deviation Score (SDS) for age.
Exclusion criteria
Exclusion criteria: - Coexisting medical problems such as celiac disease. - Thyroid function test last determined > 1 year ago. - Dietary restrictions. - Fasting blood glucose level > 10 mmol/l or < 3.8 mmol/l requiring intervention during the morning of study days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak glucose level in the 3-hour clinical observation period following the standard and test meal. | — |
Secondary
| Measure | Time frame |
|---|---|
| Glucose excursion at 30-minute intervals from baseline till 180 minutes after each meal, number of hypoglycaemic events (blood glucose level < 3.8 mmol/l) in the 3-hour clinical observation period following the meals, time to peak glucose level and the proportion of time blood glucose level exceeded 10 mmol/l. | — |
Contacts
Public ContactD.C.M. Kaay, van der
P/a Dutch Growth Foundation, Westzeedijk 106
Outcome results
None listed