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The effect of Continuous Positive Airway Pressure (CPAP) on the collapsed lung during single-lung-ventilation in patients undergoing robot-assisted thoracoscopic esophageal reseection: pulmonary complications, local and systemic cytokine production.

The effect of Continuous Positive Airway Pressure (CPAP) on the collapsed lung during single-lung-ventilation in patients undergoing robot-assisted thoracoscopic esophageal reseection: pulmonary complications, local and systemic cytokine production.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON21972
Enrollment
30
Registered
2006-03-28
Start date
2006-04-05
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Continuous Positive Airway Pressure (CPAP) to the collapsed lung during single-lung-ventilation vs no CPAP.

Sponsors

University Medical Center Utrecht (UMCU), Department of Surgery
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with resectable carcinoma of the esophagus or junction that will undergo robot-assisted thoracoscopic esophago-lymphadenectomy with gastric conduit formation; 2. ASA classification < 4; 3. Written informed consent.

Exclusion criteria

Exclusion criteria: 1. Moderate/severe lung function impairment ascertained by pulmonary function tests, requiring high dose steroid therapy; 2. No epidural catheter.

Design outcomes

Primary

MeasureTime frame
Local and systemic cytokine production.—

Secondary

MeasureTime frame
1. Pulmonary complications; 2. Ventilation time; 3. ICU stay; 4. Hospital stay.—

Contacts

Public ContactR. Hillegersberg, van

University Medical Center Utrecht (UMCU) Department of Surgery G04.228

r.vanhillegersberg@umcutrecht.nl+31 (0)88 7558074

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)