1. Pain
Conditions
Interventions
Transcraniele magnetische stimulatie met zwakke velden.
Sponsors
UMCG
Postbus 196
9700 AD Groningen
the Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: 1. 18-80 years old; 2. subjectively healthy; 3. neuropathic pain (patients only).
Exclusion criteria
Exclusion criteria: 1. Neurological (e.g. epilepsy) history (volunteers only); 2. Neurological history apart from neuropathic pain (patients only); 3. Psychiatric history; 4. Recent use (within four weeks) of antidepressants, antiepileptic drugs or prescription psychopharmaca; 5. Excessive use of: coffee (>10 units per day), alcohol (>10 units per day); 6. Recent use (within four weeks) of cannabis or any other non-prescription psychopharmaca; 7. Presence in the body of MRI incompatible implants, electronic implants (e.g. cardiac pacemakers),or connectors of electronic equipment (e.g. electrodes).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety and tolerability in healthy volunteers and patients: any self-reported experiences are recorded. Small neuropsychological tests are performed such as long number recollection and reverse recital of the months of the year. Neuropathic pain model in healthy volunteers and neuropathic pain in patients: visual analogue scale of pain intensity. Nociceptive pain model in healthy volunteers and patients: warmth detection threshold (oC) and heat pain threshold (oC). | — |
Secondary
| Measure | Time frame |
|---|---|
| During the pain studies (as opposed to the safety and tolerability studies where this is the main endpoint) all subjects are debriefed about whether any sensations were perceived during the experiment. | — |
Contacts
Public ContactR. Kortekaas
Postbus 196
Outcome results
None listed