Subarachnoid haemorrhage (SAH), cerebral vasospasm, transcutaneous electrical neurostimulation (TENS), sympathetic nervous system. Subarachnoidale bloeding (SAB), cerebrale vaatspasmen, transcutane electrische neurostimulatie (TENS), sympathisch zenuwstelsel.
Conditions
Interventions
The first part of the study concerns the finding of an optimal
frequency. When the stimulation will be started, optimal parameters will
be sought. The pulse-width will be 200ms in all patients. The cu
Sponsors
University Medical Center Groningen,
Departments of neurosurgery, clinical neurophysiology, neurology and epidemiology
Eligibility
Inclusion criteria
Inclusion criteria: 1. Confirmed aneurysmatic subarachnoid hemorrhage; 2. Cerebral vasospasm demonstrated by TCD, defined as a MCA/ICA ratio >3; 3. Aneurysm is treated with a surgical or endovascular procedure; 4. Age > 18 years; 5. Treatment can be started promptly; 6. Informed consent signed by patient or family.
Exclusion criteria
Exclusion criteria: 1. History of cervical spine or skull-base surgery; 2. Known adverse reaction to TENS-pads; 3. The presence of any implanted electronic device (including pacemakers); 4. Pre-existing disease that can obscure follow-up; 5. Unacceptable interference with cardiographic registration (in case intensive care is necessary); 6. Insuficient temporal bony windows.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cerebral bloodflowvelocities as measured with TCD. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Cerebral oxygenation determined by NIRS; 2. Neurological examination, combined with CT image; 3. Bloodpressure and pulse; 4. Registration of adverse events. | — |
Contacts
Public ContactM. Laan, ter
Hanzeplein 1, PB 90.001
Outcome results
None listed