Impaired connectvity
Conditions
Interventions
Two electromagnets are fitted over the EEG/NIRS cap. Magnetic field flux densities <5mT are applied to the head. The microTMS stimulus will consist of pulsed magnetic stimulation. Pulses will consist
Sponsors
University Medical Center Groningen
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult healthy volunteers; 2. Native Dutch speaker; 3. Age 18-80.
Exclusion criteria
Exclusion criteria: 1. Psychiatric or neurological disease, present or past; 2. Visual or hearing limitations that can not be corrected for; 3. Alcohol or drug addiction; 4. Excessive intake of coffee (>10 units per day) or alcohol (>10 units per day); 5. Recent use of alcohol (within 1 day); 6. Recent use (within four weeks) of cannabis or any other non-prescription psychopharmaca; 7. Presence in the body of MRI-incompatible implants, electronic implants (e.g. cardiac pacemakers), or connectors of electronic equipment (e.g. electrodes); 8. Pregnancy, lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The change in effective brain connectivity estimated by DCM for EEG; 2. The differences in concentrations of oxygenated (HBo) and de-oxygenated blood before, during and after the treatment (as estimated from NIRS measurements). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The estimated coherence of EEG recordings between electrodes; 2. The ERP from EEg recordings; 3. The accuracy from the cognitive test; 4. The accuracy from the Digit symbol substitution test; 5. The differences in concentrations of oxygenated (HBo) and de-oxygenated blood before, during and after the treatment (as estimated from NIRS measurements). | — |
Contacts
Public ContactCurcic-Blake Branislava
Antonius Deusinglaan 2
Outcome results
None listed