Perioperative changes in the microvascular perfused boundry region in patients undergoing coronary artery bypass grafting

The influence of different biocompatible-Perioperative changes in the microvascular perfused boundry region in patients undergoing coronary artery bypass grafting

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON21929

Enrollment

Registered

2013-10-25

Start date

2013-09-01

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Microcirculation, Glycocalyx, Cardiac surgery, Heparin, Cardiovascular disease

Interventions

none

Eligibility

Inclusion criteria

Inclusion criteria: adult patients (age 18-85 years) undergoing CABG surgery, informed consent

Exclusion criteria

Exclusion criteria: Re-operation, emergency operation, patients with diabetes mellitus type 1, patients with a history of hematologic or hepatic diseases or renal replacement therapy, patients with a Body Mass Index (BMI) over 35 kg/m2

Design outcomes

Primary

Measure	Time frame
Perioperative changes in the perfused boundry region (PBR) of the sublingual microvasculature	—

Secondary

Measure	Time frame
Perioperative changes in plasma markers for shedding of the glycocalyx such as heparan sulfate, hyaluronic acid and syndecan-1	—

Contacts

Public ContactA.B.A. Vonk

Dept. of Cardio-thoracic surgery VU University Medical Center De Boelelaan 1117

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)