Acute myeloid leukemia Acute myeloide leukemie
Conditions
Interventions
1. Blood and stool samples will be collected
2. CT-scan of abdomen at day 10-12
3. Mucositis score will be determined
4. DNA isolation from normal peripheral blood.
Sponsors
Prof.dr. E. Vellenga
Dept. of Hematology
University Medical Center Groningen
P.O. Box 30.001
9700 RB Groningen
The Netherlands
Phone: +31 50 361 61 61
E-mail: e.vellenga2int.umcg.nl
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18-70 years; 2. Diagnosed with AML and treated with intensive chemotherapy.
Exclusion criteria
Exclusion criteria: Ineligible to perform the tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Defining the severity of epithelial dysfunction measured with mucositis score, the stool volume, the calprotectin level in the stool, the urinary Cr EDTA excretion and serum IL-8 and CRP levels; 2. Typhlitis based on clinical symptomatology and CT-scanning abdomen. | — |
Secondary
| Measure | Time frame |
|---|---|
| Before and after treatment with chemo different parameters will be examined. | — |
Contacts
Public ContactE. Vellenga
University Medical Center Groningen (UMCG), Department of Hematology, P.O. Box 30001
Outcome results
None listed