Antiphospholipid syndrome, thrombosis
Conditions
Interventions
Patients will endure 1 finger stick procedure and 1 venepuncture,
Sponsors
Dutch Thrombosis Foundation
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Age 18 years and older - Previously confirmed APS, diagnosed in accordance with the Sydney criteria22 - Receiving VKA during at least 3 months - Willing and be able to understand the study information and sign the informed consent form
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective of this study is to determine discrepancies between INR measurements with Coaguchek and Coagulometer in lupus anticoagulant positive APS patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary objective of this study is to investigate which antiphospholipid antibodies correlate with the found INR discrepancies. Furthermore, we will look into the differences within two different groups of APS patients: triple positive APS patients (tested positive for at least lupus anticoagulant, anti-cardiolipin antibodies and anti-ß2-glycoprotein I antibodies) and non-triple positive patients (tested positive for at least lupus anticoagulant). | — |
Contacts
Public ContactTessa Noordermeer
UMC Utrecht
Outcome results
None listed