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HELPFul

Discovery and validation of diagnostic biomarkers for left ventricular diastolic dysfunction and HEart faiLure with Preserved circulation ejection Fraction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON21717
Enrollment
3000
Registered
2016-04-14
Start date
2016-06-01
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diastolic dysfunction of the heart, eventually evolving into heart failure with preserved ejection fraction, Coronary vascular disease, including both macro- and microvascular coronary disease

Interventions

Sponsors

nvt
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: • Patients in the cardiology outpatient clinic (CCN) who are being evaluated with an echocardiography because of screening or referral from a general practitioner • Age >= 45 year • Patient is willing and able to provide written informed consent for participation in this study • The inclusion criteria for cases match the criteria for diagnosis of LVDD or HFpEF. The inclusion criteria for the subjects included in the random sample are similar for cases irrespective of their echocardiography findings.

Exclusion criteria

Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: • Patients from whom no informed consent is obtained • Incapacitated adults: language barriers or other obstacles for full understanding of the study objectives • Patients with former cardiac procedures. • Patients with congenital heart disease

Design outcomes

Primary

MeasureTime frame
The primary outcome will be categorical: degree of LVDD and HFpEF yes or no

Contacts

Public ContactHELPFul study team helpful@umcutrecht.nl

UMC Utrecht

helpful@umcutrecht.nl0887550760

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)