Vitamin D deficiency, Vitamine D deficiëntie
Conditions
Interventions
The drawing of a single venous blood sample, which is standard care as part of the Vitamin D protocol.
Sponsors
Medisch Centrum Leeuwarden
Eligibility
Inclusion criteria
Inclusion criteria: The study population comprises residents of 13 somatic and psycho-geriatric nursing homes. Nursing home residents will be screened for eligibility based on the inclusion criteria. In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Subjects must be over 18 years of age. - Subjects must have received vitamin D supplementation according to protocol for at least 4 months (a single oral loading dose of 200,000 IU cholecalciferol followed by at least one maintenance dose of 100,000 IU after 13 weeks).
Exclusion criteria
Exclusion criteria: Not applicable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary aim of this study is to determine the efficacy of the established cholecalciferol dosing regimen (a single oral loading dose of 200,000 IU cholecalciferol followed by 100,000 IU orally every 13 weeks) in obtaining and maintaining an adequate serum 25-hydroxyvitamin D level between 75 and 220 nmol/L in somatic and psycho-geriatric nursing home residents. | — |
Secondary
| Measure | Time frame |
|---|---|
| A second aim of this study is to assess the additional effect of the vitamin D dosing regimen on serum PTH and calcium levels, and to determine the influence of (known) variables as possible effect modifiers on the serum 25-hydroxyvitamin D level outcome. | — |
Contacts
Public ContactM.L. Toren
Medisch Centrum Leeuwarden
Outcome results
None listed