Anxiety Personality disorders co-morbidity angst persoonlijkheidsstoornis comorbiditeit
Conditions
Interventions
In treating the Axis I anxiety disorder the recommendations of the Dutch guideline for Anxiety disorders will be followed. Treatment will consist of maximally 30 sessions of cognitive behavioral thera
Sponsors
Leiden University
Pieter de la Court gebouw
Wassenaarseweg 52
2333 AK Leiden
tel: 071-5274003
Eligibility
Inclusion criteria
Inclusion criteria: Patients with an Axis I anxiety disorder (of panic disorder with/without agoraphobia, agoraphobia without a history of panic disorder, obsessive-compulsive disorder, social phobia, generalized anxiety disorder) as primary diagnosis, according to DSM-IV-TR. If there is an Axis I anxiety disorder present as primary diagnosis, patients will be screened for a co-occurring cluster C personality disorder (dependent personality disorder, avoidant personality disorder, obsessive-compulsive personality disorder), using a self-report questionnaire, the ADP-4 as a screener (Scotte et al., 1998). When this screening list is positive for a Cluster C personality disorder, co-morbidity of an Axis II cluster C personality disorder will be formally established using the corresponding part of the Structured Clinical Interview for DSM-IV Axis II Personality Disorders Further inclusion criteria are as follows: 1. Patients have to be 18 years of age or older 2. Patients have to be fluent in the Dutch language 3. Treatment has to be voluntary 4. There has to be informed consent, both for the treatment itself and for participation in the research project.
Exclusion criteria
Exclusion criteria: Exclusion criteria are as follows: 1. Evidence of a mental retardation with an IQ less then 70 2. Signs of acute danger to self or others and/or (need for) involuntary treatment 3. A history of psychotic disorders 4. Patients already in therapy and receiving a psychological treatment for their anxiety or Cluster C personality disorder 5. Patients who have a cluster A or cluster B personality disorder 6. Patients who have a major depressive disorder 7. Patients with a specific phobia (because of relative ‘simplicity’ and short duration of treatment) or post-traumatic stress disorder (because of relative ‘complexity’ and overall long duration of treatment(8) patients who are incapable of filling in the different questionnaires.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| As primary outcome measure significant changes in general anxiety as assessed with the Beck Anxiety Inventory (BAI) (Beck & Steer, 1990) will be used. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary measures will assess: - more specific forms of anxiety (PSWQ, ASI, FQ, LSAS, PI-R) - general psychopathology (SCL-90R) - interpersonal problems (IIP, WAV) - personality pathology (ADP-IV, NEO-PI-R, NVM) - cognitive schemas and schema modes (SV-1, PDBQ, YPI, YRAI, YCI, SMI-R) - quality of life (WHOQOL-Bref, EQ-6D) - direct and indirect costs (TIC-P) - patient satisfaction (GGZ-thermometer). Remission from anxiety and AXIS II disorder is measured with the MINI and the SCID-II at post treatment and at follow up. Also an implicit computer task will be used to measure the decrease of personality pathology. To evaluate the efficacy of the treatment modalities a cost analysis will be performed using data from a medical consumption diary kept by the patient. | — |
Contacts
Public ContactV.C. Braeckman
Dimence Nico Bolkesteinlaan 1
Outcome results
None listed