Obesity
Conditions
Interventions
Subjects will visit the university twice and during each visit they will stay in the respiration chamber for two days and nights (48hrs). During one of these visits subjects will sleep normally
during the other visit SWS will be suppressed. Subjects will be asked for their usual bedtimes during the week. They will be in a partly time-blinded surrounding and told to go to sleep or get out of
Sponsors
No sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy men and women; 2. A Body Mass Index (BMI) between 24-27 kg/m2; 3. Age of 20-30 years; 4. Short sleepers (les than 7 hours) and normal sleepers (7 to 8 hours) are included.
Exclusion criteria
Exclusion criteria: Exclusion criteria for subjects are apart from age, BMI and sleep duration: 1. Smoking; 2. Being on medication (except the use of contraception); 3. Excessive alcohol consumption; 4. Excessive exercise; 5. Not being weight stable; 6. Being dietary restraint (assessed by the Three Eating Questionnaire (TFEQ));
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Effect of spontaneous sleep duration cq sleep alteration on: total energy expenditure, AEE (physical activity is measured with a Doppler radar and Tracmor system) and substrate oxidation in the respiration chamber; 2. Feelings of hunger, satiety and rewarding values of food: food intake; 3. The endocrinological parameters: melatonin, cortisol, ghrelin, leptin, growth hormone, insulin, glucose, adrenalin and noradrenalin and orexin A; 4. Body temperature (measured with a CorTemp™ Data Recorder). | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes. | — |
Contacts
Public ContactRick Hursel
Maastricht University Dept. Humane Biology PO Box 616
Outcome results
None listed