Effect of optical quality on retinal thresholds

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON21576

Enrollment

Registered

2017-07-31

Start date

2018-01-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Phakic and pseudophakic POAG and PACG patients and phakic PAC patients scheduled for CLE, who visit the ophthalmology clinic at University Medical Center Groningen, that have provided the signed informed consent form and meet the inclusion-exclusion criteria. Healthy subjects between ages 50 and 75, who have provided the signed informed consent form and returned the questionnaire with results which do not indicate ophthalmic abnormalities.

Exclusion criteria

Exclusion criteria: POAG patients Visual acuity less than 0.8 Axial length lower than 23mm History of closed or blocked angle Myopia higher than 5D For pseudophakic patients only, IOL model implanted different than Tecnis Monofocal, Model ZCB00 Phakic PACG patients Visual acuity less than 0.8 Axial length higher than 23mm For pseudophakic patients only, IOL model implanted different than Tecnis Monofocal, Model ZCB00 Phakic PCA scheduled for CLE Visual acuity less than 0.8 Non-glaucomatous visual field loss IOL model to be implanted different than Tecnis Monofocal, Model ZCB00 Axial length higher than 23mm Healthy Subjects Visual acuity less than 0.8 Corneal refractive (LASIK, LASEK, RK, PRK, etc.) Any visual field loss Intraocular pressure above 21 mmHg Positive family history of glaucoma

Design outcomes

Primary

Measure	Time frame
Retinal sensitivity thresholds, measured by means of perimetry, as a function of ocular aberrations.	—

Secondary

Measure	Time frame
Change in retinal sensitivity thresholds, measured by means of perimetry, as a function of ocular aberrations before and after clear lens extraction in PAC patients Other Corneal aberrations, ocular biometry, ocular scatter, intraocular pressure, visual acuity and refraction. Cases and controls are matched for age and gender; visual field damage and refraction are used for descriptive statistics, to characterize the study population.	—

Measure

Time frame

Change in retinal sensitivity thresholds, measured by means of perimetry, as a function of ocular aberrations before and after clear lens extraction in PAC patients Other Corneal aberrations, ocular biometry, ocular scatter, intraocular pressure, visual acuity and refraction. Cases and controls are matched for age and gender; visual field damage and refraction are used for descriptive statistics, to characterize the study population.

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Contacts

Public ContactL. Scanferla

l.scanferla@umcg.NL

Outcome results