The pharmacokinetics of nimodipine, intravenous and orally, in patients with subarachnoidal hemorrhage admitted in the intensive care.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON21573

Enrollment

Registered

2007-01-19

Start date

2006-12-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

subarachnoidal hemorrhage treatment in intensive care

Interventions

Bloodsamples according to strict time protocol during treatment.

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients admitted on the ICU with subarachnoidal hemorrhage (SAB), treated according to our SAB-protocol; 2. Adults aged 18 - 70 years old.

Exclusion criteria

Exclusion criteria: 1. Pregnancy; 2. Expected mortality < 24 hours; 3. Severe hepatic function disorders; 4. Use of medication with know interaction in relation to nimodipine.

Design outcomes

Primary

Measure	Time frame
1. Pharmacokinetics of nimodipine in this specific group of patients; 2. Variability of bio-availability of orally administred nimodipine.	—

Contacts

Public ContactB.M. Kors

VU medisch centrum Afdeling intensive care volwassenen Boelelaan 1117

bm.kors@vumc.nl+ 31 20 4443900

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)