The effect of IV antibiotics on gut flora during an episode of fever in children with cancer.

The effect of systemic antibiotics on the microbiota in the feces during febrile neutropenia in pediatric patients with cancer.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON21552

Enrollment

Registered

2016-03-16

Start date

2015-06-18

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Systemic antibiotics, microbiota, pediatric patients with cancer, febrile neutropenia.

Interventions

Collecting fecal samples obtained from feces in commode chair.

Eligibility

Inclusion criteria

Inclusion criteria: - Pediatric patients with cancer hospitalised in University Medical Centre Groningen - Reason of hospitalization is febrile neutropenia - Active treatment with systemic antibiotics

Exclusion criteria

Exclusion criteria: - No defecation within the first three days of hospitalization

Design outcomes

Primary

Measure	Time frame
- Number of specific bacterial groups in feces of pediatric patients	—

Secondary

Measure	Time frame
- The difference in diversity of the microbiota before and after treatment - Type of systemic antibiotics - Laboratory values (Hb, CRP, leukocytes) - Blood cultures - Temperature - Type of nutrition	—

Contacts

Public ContactW.J.E. Tissing

Pediatric Oncologist and Hematologist Hanzeplein 1

w.j.e.tissing@umcg.nl+31 (0)50 3614213

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)