Treatment of severe fatigue after stroke. A study of cognitive therapy and physical exercise training in eight rehabilitation centres in the Netherlands.

Effectiveness of Cognitive and Graded Activity Training (COGRAT) on post-stroke fatigue. A multi-center study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON21507

Enrollment

Registered

2011-01-20

Start date

2007-05-16

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke fatigue Cognitive Rehabilitation graded activity CVA vermoeidheid cognitieve revalidatie

Interventions

COGRAT consist of 2 arms given alongside during 12 weeks. 1. Cognitive strategy training: Frequency

1x week for 2 hours (& homework) in small groups (max 4 patients). It consists of: A. Patient education on fatigue after stroke and sleep hygiene

B. Gaining insight into the individual activity and fatigability pattern by logging activities and fatigue

C. Cognitive strategy training in order to prevent fatigue and manage existing fatigue. These strategies are: modification of activity patterns, improvement of planning abilities and the use of relaxa

D. Cognitive behavioural Therapy (CBT) to enhance behavioural change and to assist in managing existing fatigue. 2. Graded Activity Training: Frequency: 2x week, for 2 hours & homework assignments.

B. Strength training

C. Stretching

Maximum heart rate and strength are increased from 40% at the beginning of the training and increased during the treatment to a maximum of 70% at the end of the 12 weeks.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Post-onset of stroke at least 4 months; 2. Age between 18 and 70 years; 3. Checklist Individual Strength (CIS) fatigue severity score of 40 or more; 4. Rivermead Mobility Index > 11/15 (able to walk independently).

Exclusion criteria

Exclusion criteria: 1. Severe cognitive impairments (severe neglect, severe memory problems, severe planning problems, denial of illness); 2. Psychopathology (clinical interview and HADS-depression score >10); 3. Severe cardiac and pulmonary disease.

Design outcomes

Primary

Measure	Time frame
Fatigue severity (Checklist Individual Strength, fatigue severity score).	—

Secondary

Measure	Time frame
1. Psychosocial well-being (SCL-90 & HADS); 2. Functional impairments (SA-SIP-30); 3. Physical condition (6 minute walking test); 4. Activity (actometers & registration); 5. Attention (SART & ANT); 6. Memory (RMBT & CVWLT); 7. Cognitive complaints (CIS-C, CFQ); 8. Coping (CISS); 9. Attribution (SES & FCS); 10. Social support (SSL).	—

Contacts

Public ContactA.M.E.E. Zedlitz

P.O. box 9104

a.zedlitz@donders.ru.nl+ 31 (0)24 3612646

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)