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Stress sensitisation and psychosis risk.

Reactivity to social stress in second generation Moroccan men and siblings of patients with psychotic disorder.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON21501
Enrollment
160
Registered
2011-06-24
Start date
2011-10-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psychosis stress experience sampling method migration psychose stress experience sampling methode migratie

Interventions

After completing the ESM data collection all participants are exposed to a social stress situation. This involves negative feedback on a personal digital profile given by (fictional) peers. It is vari

Sponsors

Maastricht University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Male; 2. Age 18-30; 3. Second generation Moroccan or native-Dutch.

Exclusion criteria

Exclusion criteria: 1. Mental retardation (IQ < 70) and/or illiteracy; 2. Diagnosis of psychotic disorder.

Design outcomes

Primary

MeasureTime frame
1. Reactivity (changes in affect and psychotic symptoms) to self-reported stress in daily life, assessed using the Experience Sampling Method (ESM); 2. Changes in affect and psychotic symptoms in response to an experimental social stress situation involving negative feedback from peers.

Secondary

MeasureTime frame
1. Group level differences in reactivity to other forms of (event related, activity) stress; 2. Differences in reactivity to an experimental social stress situation as dependent on the ethnicity of the peers causing the stress. Controlling for: Family structure, SES, urbanicity, IQ (non-verbal), IQ (verbal), non-clinical psychotic symptoms, depression score, social defeat score, self-other schemas, childhood trauma, psychopathy, discrimination, perception of living environment, self-esteem, childhood care and abuse, drug use, life events, bullying, ethnic identity, perceived effects of stigma.

Contacts

Public ContactM.J. Gevonden

Meibergdreef 9

m.j.gevonden@amc.uva.nl+31 (0)20 5661644

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)