Dynamic MRI with mapping of T1-values as indicators of disease activity in luminal Crohn’s disease.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON21489

Enrollment

Registered

2010-02-04

Start date

2009-02-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's disease, ziekte van Crohn

Interventions

Longer MRI scan due to extra dynamic sequence.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Proven Crohn’s disease (by endoscopy or histopathology); 2. Scheduled to undergo an ileocolonoscopy as part of their clinical follow-up; 3. Scheduled to undergo a MRI.

Exclusion criteria

Exclusion criteria: 1. Under 18 years of age; 2. General contraindications to MRI (claustrophobia, pregnancy, renal insufficiency, pacemakers).

Design outcomes

Primary

Measure	Time frame
The main study parameter will be the accuracy of detecting disease activity and efficacy of DCE MRI with T1 mapping at MR in patients with proven Crohn’s disease as compared to ileocolonoscopy with histopathology.	—

Secondary

Measure	Time frame
The secondary endpoints will be the comparison of DCE MRI with T1-mapping as compared to CDEIS, CRP, CDAI.	—

Contacts

Public ContactM.L.W. Ziech

Meibergdreef 9

m.l.ziech@amc.uva.nl+31 (0)20 5663740

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)