Hepatocellular Carcinoma Colorectal Liver Metastasis Hepatocellulair carcinoom Colorectale lever metastase
Conditions
Interventions
CT-guided percutaneous liver tumor ablation
Sponsors
University Medical Center Groningen
Eligibility
Inclusion criteria
Inclusion criteria: Indication to be treated by CT-guided percutaneous liver ablation • Age >18 years • Able to read Dutch language • Signed written informed consent • Physical and mental state allow general anesthesia as judged by the anesthesiologist
Exclusion criteria
Exclusion criteria: Every patient who qualifies for a percutaneous ablation of a liver tumour, can participate in the study except for patients in whom intravenous contrast cannot be administered. This can happen in patients in whom no contrast can be given despite preventive measures like untreatable contrast allergy or severe kidney dysfunction in whom even pre-hydration and other measures according to the UMCG contrast-nephropathy protocol do not allow i.v. contrast injection. Since precision is an important issue in this study, liver tumors need to be precisely located and measured. Therefore precise demarcation of the tumor in relation to the surrounding liver parenchyma is essential and this requires the use of i.v. contrast. Rarely, tumors are visible on non-contrast-enhanced CT scans. Patients with absolute contraindications for contrast administration will nevertheless be treated by percutaneous ablation, but we do not want to include these patients in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of needle insertions to reach an adequate target position. | — |
Secondary
| Measure | Time frame |
|---|---|
| -1- deviation from predefined optimal tip-of-needle position based on lateral displacement (3D), angle deviation and longitudinal displacement, -2- time span needed to obtain adequate position, -3- number of control CT scans during the procedure to check the needle position, including calculation of radiation dose, -4- completeness of ablation zone as evaluated during the standard one-week post-procedural CT scan. | — |
Contacts
Public ContactW.J. Heerink
HPC: EB45
Outcome results
None listed