Advanced lung ultrasound to differentiate pneumonia and atelectasis in ICU patient

Advanced lung ultrasound to differentiate pneumonia and atelectasis in ICU patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON21456

Enrollment

118

Registered

2020-12-15

Start date

2018-10-08

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia, Atelectasis

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Adult (18 years) patients admitted to the ICU with consolidation on chest X-ray

Exclusion criteria

Exclusion criteria: ARDS, pulmonary contusion, contact isolation, COVID-19

Design outcomes

Primary

Measure	Time frame
Sensitivity, Specificity, Positive/Negative Predictive Values, Positive/Negative Likelihoodratios for pneumonia (for ultrasound parameters alone and within a clinical prediction score/decision tree) assessed by lung ultrasound (flow measured by color doppler imaging and the dynamic air bronchogram). Pneumonia will be defined as the clinical diagnosis established by the treating physician when all clinical data necessary to establish a diagnosis are available (cq. CRP, leukocytes, Temperature, physical examination, Imaging summary (CXR or CT) and gram stain information). The timepoint for this diagnosis will be set at within 24 hours after the gramstain is available. The ultrasound will be performed within 24 hours of chest X-ray and the ultrasound diagnosis will be made directly at the bedside after completion of the ultrasound exam without delay.	—

Measure

Time frame

Sensitivity, Specificity, Positive/Negative Predictive Values, Positive/Negative Likelihoodratios for pneumonia (for ultrasound parameters alone and within a clinical prediction score/decision tree) assessed by lung ultrasound (flow measured by color doppler imaging and the dynamic air bronchogram). Pneumonia will be defined as the clinical diagnosis established by the treating physician when all clinical data necessary to establish a diagnosis are available (cq. CRP, leukocytes, Temperature, physical examination, Imaging summary (CXR or CT) and gram stain information). The timepoint for this diagnosis will be set at within 24 hours after the gramstain is available. The ultrasound will be performed within 24 hours of chest X-ray and the ultrasound diagnosis will be made directly at the bedside after completion of the ultrasound exam without delay.

—

Secondary

Measure	Time frame
Comparison of clinical prediction score based on clinical and ultrasound parameters for pneumonia and correlation with PF-ratio expressed as Sensitivity, Specificity, Positive/Negative Predictive Values, Positive/Negative Likelhoodratios and ICC. The exact same timeline in regards to measurement methods and timepoints will be used as for the primary outcome.	—

Contacts

Public ContactMark Haaksma

Amsterdam UMC

m.haaksma@amsterdamumc.nl0648072416

Outcome results