medication safety
Conditions
Interventions
The intervention consists of an extensive medication screening using clinical rules each week
Sponsors
Gerontopharmacology, Zuyderland Medical Centre
Eligibility
Inclusion criteria
Inclusion criteria: The study population consists of older people admitted unplanned to the hospital and fulfilling the following criteria: 1) aged 60 years and over, 2) ability to give informed consent, 3) polypharmacy (> 5 drugs chronically), 4) at least two signals from the trigger list as proposed by the report "Eindrapport medicatieveiligheid".
Exclusion criteria
Exclusion criteria: The intention of the study is to include the normal population offered to the hospital as much as possible. However, due to legal constraints and to avoid certain biases potential subjects who meets any of the following criteria will be excluded from participation in this study: intentional intoxications, patients treated with cytostatics, patients with a life expectancy of less than 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the number of readmissions during the year after admission. An economic evaluation and quality of life analysis is part of the proposal. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints of this study are; number of emergency department contacts, number of nursing home admissions during the year after patients’ inclusion in the study, death, time to hospital readmission, the number of hospital readmissions during the following 30, 180 and 365 days, the number of medication-related hospital (re) admissions, the combined endpoint hospital readmissions, emergency department contacts, nursing home admissions or death, total costs (from a societal perspective) and the Quality Adjusted Life Years (QALY) score. | — |
Contacts
Public ContactVanja Milosevic
Zuyderland MC
Outcome results
None listed