esophageal cancer, esophagectomy, nutrition, postoperative complications, pulmonary complications, anastomic leakage, Quality of life
Conditions
Interventions
Early oral feeding after an esophagectomy. Patients will start a liquid oral diet directly postoperatively.
Control group: enteral feeding via a jejunostomy for 2 weeks after surgery.
Sponsors
Catharina Hospital Eindhoven
Eligibility
Inclusion criteria
Inclusion criteria: - Patients that undergo a (minimally invasive) esophagectomy with intrathoracic anastomosis. - written informed consent - age >18 years
Exclusion criteria
Exclusion criteria: - Inability for oral intake - Inability to place a surgical feeding jejunostomy - Mental retardation - Swallowing disorder - Achalasia - Malnutrition (defined as >15% weight loss just before start of the surgery)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Functional recovery | — |
Secondary
| Measure | Time frame |
|---|---|
| - Pulmonary complications (Pneumonia, Acute respiratory distress syndrome (ARDS), respiratory insufficiency requiring treatment) - Anastomotic leakage (clinically and amylase levels in drain fluid) - Nutritional status (weight loss, intake) - Need for parenteral feeding/ placement of a nasojejunal feeding tube - Need for additional surgical, radiological or endoscopic interventions - 30-day surgical complications (classified according to Clavien-Dindo) - Other complications requiring treatment (i.e. urinary tract infection) - Need for ICU admission and total length of ICU stay - Quality of life | — |
Contacts
Public ContactGijs H.K. Berkelmans
Department of Surgery, Catharina Hospital
Outcome results
None listed