None listed
Conditions
Interventions
The main study parameters will be patterns of cardiovascular dysfunction in different groups of RA patients using cardiac imaging techniques echocardiography and cardiac MRI. To assess cardiovascular
Sponsors
Medisch Spectrum Twente, Enschede, The Netherlands
Department of Cardiology and Department of Rheumatology
Eligibility
Inclusion criteria
Inclusion criteria: Participants in this study will be selected from a large database of RA patients at the rheumatology department. Three groups of patients with rheumafactor positive and anti-CCP positive rheumatoid arthritis will be selected. The first group consists of 30 patients with new onset rheumatoid arthritis (early RA group, 6 months). The third group consists of 30 patients with longstanding rheumatoid arthritis (longstanding RA, > 15 years disease duration, erosive disease, expert based stable low disease activity > 6 months). The age of the study population is 18-75 year
Exclusion criteria
Exclusion criteria: Exclusion criteria: previous CV disease, current smoking, age 75 years, pregnancy, history of kidney dysfunction (GFR 6.5 mmol/l), history of hypertension (systolic pressure > 140 mmHg, diastolic pressure > 90 mmHg) or use of antihypertensive medication, history of diabetes mellitus (fasting glucose level > 7.0 mmol/l), body mass index > 30 kg/m2, claustrophobia or other exclusion criteria for MRI such as implanted metal materials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| With this pilot study we want to determine parameters that are useful for further follow-up studies in patient with RA in assessing cardiovascular risk with cardiac imaging techniques. | — |
Contacts
Public ContactE.O.F. Gorselen, van
Haaksbergerstraat 55
Outcome results
None listed