Atropine-effect during propofol/remifentanil induction.

Evaluation of the beneficial effects of the administration of atropine during propofol/remifentanil induction of general anesthesia on hemodynamics, microvascular blood flow and tissue oxygenenation.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON21251

Enrollment

Registered

2012-09-19

Start date

2012-09-17

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hemodynamics (cerebral) tissue oxygenation general anesthesia

Interventions

All patients will receive a standard anesthesia based on propofol and remifentanil. During the induction of anesthesia patients will randomly receive either atropine 500ug or saline. If necessary, hem

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients requiring general anaesthesia; 2. Patients age 18 years and older; 3. Patient and surgical procedure appropriate for treatment with atropine.

Exclusion criteria

Exclusion criteria: 1. Patients refusal; 2. Pregnancy; 3. Patients age < 18 years; 4. Patients in which atropine is contra-indicated.

Design outcomes

Primary

Measure	Time frame
Hemodynamics and tissue oxygenation.	—

Secondary

Measure	Time frame
Requirement of other vasoactive medication.	—

Contacts

Public ContactR. Spanjersberg

Hanzeplein 1

r.spanjersberg@umcg.nl+31 (0)50 3611158

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)