Neuropsychological deficits as a consequence of childhood cancer Neurospychological monitoring, cognitive deficits, pediatric cancer
Conditions
Interventions
None listed
Sponsors
The Princess Máxima Centre
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: • New primary diagnosis of brain tumor, other solid tumor, or hemato-oncological condition • Age between 6 and 18 years old at diagnosis • Followed at the Princess Máxima Centre for Pediatric Oncology
Exclusion criteria
Exclusion criteria: • No signed informed consent • Insufficient knowledge of the Dutch language to perform the neuropsychological assessment or complete questionnaires • Significant visual, motor, or developmental problems and thus alternative neuropsychological assessments would be needed (i.e., blindness, deafness, profound developmental delay) • Patients receiving palliative therapy or end-of-life care • Treating physician advises against inclusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Age-standardized performance on functional outcome measures (intelligence, memory, academics, school functioning, adaptive functioning, social-emotional functioning) and broader aspects of neuropsychological functioning (attention, executive function, working memory, processing speed, visual-spatial/motor, quality of life) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary and tertiary study parameters/endpoints: Longitudinal trajectories on brief monitoring measures (1), clinical, biological, and psychosocial risk factors (2), mean performance and frequency of impairments on neuropsychological measures (3), and acceptability and feasibility of a monitoring program (4). | — |
Contacts
Public ContactMarisa Huisman
Prinses Maxima Centrum
Outcome results
None listed