No health problem
Conditions
Interventions
In the study, subjects will receive single doses of placebo and cocaine HCL 300 mg according to a double blind, cross-over design. In this placebo-controlled within subject study with 2 conditions, s
Sponsors
J. G. Ramaekers
Maastricht University
Eligibility
Inclusion criteria
Inclusion criteria: - Subjects must have used cocaine on at least 12 separate occasions during the past two years; - Good physical and mental health as determined by medical history and medical, ECG and laboratory examination; - BMI between 19 and 29 m2/kg; - Use of appropriate contraception; - Written informed consent; - Age between 18-40 (inclusive)
Exclusion criteria
Exclusion criteria: - Pregnancy or lactation; - Cardiovascular abnormalities as assessed by standard ECG; - Excessive alcohol use, defined as drinking more than 21 glasses of alcohol per week; - History of drug abuse (other than the use of cocaine) or addiction; - Hypertension (diastolic> 90; systolic> 140); - History of psychiatric and neurological disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Creativity measures | — |
Secondary
| Measure | Time frame |
|---|---|
| Other measures (e.g. face recognition) and questionnaires | — |
Contacts
Public ContactJ.G. Ramaekers
Maastricht University Dept of Neuropsychology & Psychopharmacology, Faculty of Psychology and Neuroscience, P.O. Box 616
Outcome results
None listed