angina pectoris
Conditions
Interventions
None. The study has a prospective (diagnostic and prognostic) observational design. At the day of inclusion 6 tubes of venous blood (60cc in total) will be withdrawn from the intravenous peripheral a
Sponsors
Meander Medical Center Amersfoort
Eligibility
Inclusion criteria
Inclusion criteria: - Patients in the cardiology outpatient clinic of the Meander Medical Center Amerfoort being evaluated because of suspected ischemic coronary disease, who will undergo radionuclide myocardial perfusion imaging (rMPI), as indicated by the treating cardiologist. - Age > 18yr
Exclusion criteria
Exclusion criteria: - Patients from whom no informed consent is obtained - Incapacitated adults: language barriers or other obstacles for full understanding of the study objectives
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parameter; Extracellular vesicle protein- and miRNA-concentration, and gene expression profiles in circulating cells. Endpoint: Objectified ischemic coronary artery disease, determined by radionuclide myocardial perfusion imaging (Rubidium-82). | — |
Secondary
| Measure | Time frame |
|---|---|
| Follow-up: all-cause mortality, cardiovascular death, non-fatal MI, coronary revascularisation, stroke, and peripheral vascular interventions. | — |
Contacts
Public ContactIngrid E.M. Bank
Meander Medical Center - Department of Cardiology
Outcome results
None listed