Does treatment of a varicocele in subfertile men result in more spontaneous pregnancies?

Does treatment of a varicocele in subfertile men result in more spontaneous pregnancies? A randomized controlled trial comparing treatment to no treatment.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON21167

Enrollment

130

Registered

2009-06-04

Start date

1998-03-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Varicocele and male subfertility

Interventions

The treatment group wil have a varicocele repair by surgery or embolisation with a follow-up of 1 year. The controls will have no treatment and a follow-up of 1 year.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Clinical varicocele grade 1-3; 2. Male subfertility as confirmed by the results of two abnormal semen analyses; 3. Male age 20-60; 4. Female partner 1 year.

Exclusion criteria

Exclusion criteria: 1. Azoospermia; 2. Normal semen analysis; 3. Other male infertility factor than varicocele; 4. Femal factor for the infertility.

Design outcomes

Primary

Measure	Time frame
Primary endpoint is spontaneous pregnancy within the 1 year follow-up period in both groups.	—

Secondary

Measure	Time frame
Secundairy endpoints are improvement of semen in both groups and predictive factors for a spontaneous pregnancy.	—

Contacts

Public ContactG.R. Dohle

Erasmus MC P.O. Box 2040

g.r.dohle@erasmusmc.nl+31-10-7033095

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)