Sarcopenia and malnutrition
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Community-dwelling and-or independent living, receiving in-home care services - Aged 65 or older - Physical ability and willingness to execute a resistance exercise program - Ability and willingness to comply with the protocol - Willingness that general practitioner will be notified on study participation - Written informed consent - Consent of the study physician
Exclusion criteria
Exclusion criteria: - Inability to understand the Dutch language - Cognitive impairment (MMSE 3) - Diagnosed degenerative neurocognitive disorders - COPD GOLD >3 - Use of total parenteral nutrition (TPN) - Active medical treatment interfering with this intervention (e.g. cancer patients following systemic and immune therapy) - Physical disabled (walking aids or mild visual impairment are not an exclusion criteria) - Current enrollment in a fixed rehabilitation program or other intervention studies - Palliative treatment or a life expectancy of = 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle strength measured by the 1-RM | — |
Secondary
| Measure | Time frame |
|---|---|
| - cognitive ability - body composition - muscle architecture - inflammation markers, glucose and insulin levels - physical performance - handgrip strength - activities of daily living - quality of life - malnutrition - daily dietary intake - daily physical activity - cognitive performance - psychosocial outcomes - cost-effectiveness - adverse events / medical status - adherence - process evaluation | — |
Contacts
Amsterdam University of Applied Sciences (AUAS) (Dutch: Hogeschool van Amsterdam (HvA))